Learn more about the life-changing impact of Cereset HIRREM® Technology through our extensive research and peer-reviewed papers.

Cereset Research-Backed Results

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Abstracts & Presentations

80+

peer-reviewed publications

16

IRB Approved Clinical Trials

9

Participants in Clinical Trials

1k+

1000+

HIRREM® is the Core Brain Technology Shared with Cereset®

How Does Cereset Work?

Cereset Research is the evolution of HIRREM®, or High-resolution, Relational, Resonance-based Electroencephalic Mirroring®, which is a research technology used for specific indications, including insomnia, PTSD, concussions, hot flashes, pain, etc. The same relaxation aspects of the technology are found in HIRREM and Cereset. We are the sole developer of this advanced core technology.

HIRREM is a precision-guided technology that permits the brain to perceive its own functionality in real time, supporting brain oscillation patterns to optimize in client-unique ways. Use of HIRREM is typically accompanied by improved sleep and other benefits. Physiological sleep is critical for health, performance, and global brain plasticity.

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Rightward dominance in temporal high-frequency electrical asymmetry corresponds to higher resting heart rate and lower baroreflex sensitivity in a heterogeneous population

Brain and Behavior

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Open label, randomized, crossover pilot trial of high-resolution, relational, resonance-based, electroencephalic mirroring to relieve insomnia

Brain and Behavior

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Functional Brain Network Changes Following Use of an Allostatic, Closed-Loop, Acoustic Stimulation Neurotechnology for Military-Related Traumatic Stress

Neuroimaging

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High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM) improves symptoms and autonomic function for insomnia: A randomized, placebo-controlled clinical trial

Brain and Behavior

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Cereset Research Standard Operating Procedures for Insomnia: A Randomized, Controlled Clinical Trial

Global Advances in integrative medicine and Health

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A Preliminary Study of the Effectiveness of an Allostatic, Closed-Loop, Acoustic Stimulation Neurotechnology in the Treatment of Athletes with Persisting Post-concussion Symptoms

Sports Medicine Open

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Successful use of closed-loop allostatic neurotechnology for post-traumatic stress symptoms in military personnel: self-reported and autonomic improvements

MMR Military Medical Research

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Reduction in menopause-related symptoms associated with use of a noninvasive neurotechnology for autocalibration of neural oscillations

Menopause

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Effects of an Allostatic Closed-Loop Neurotechnology (HIRREM) on Brain Functional Connectivity Laterality in Military-Related Traumatic Stress

Neuroimaging

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Restful Sleep for Optimum Performance and Reduction of Post-Traumatic Stress Disorder

Homeland defense and security information analysis center 

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Pilot Trial of a Noninvasive Closed-Loop Neurotechnology for Stress-Related Symptoms in Law Enforcement: Improvements in Self-Reported Symptoms and Autonomic Function

Global Advances in integrative medicine and Health

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Improvements in Heart Rate Variability, Baroreflex Sensitivity, and Sleep After Use of Closed-Loop Allostatic Neurotechnology by a Heterogeneous Cohort

Frontiers in Public Health

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A bihemispheric autonomic model for traumatic stress effects on health and behavior

Frontiers in psychology

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Use of an allostatic neurotechnology by adolescents with postural orthostatic tachycardia syndrome (POTS) is associated with improvements in heart rate variability and changes in temporal lobe electrical activity

Experimental Brain Research

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Clinical, hemispheric, and autonomic changes associated with use of closed-loop, allostatic neurotechnology by a case series of individuals with self-reported symptoms of post-traumatic stress

BMC psychiatry

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HIRREM™: a noninvasive, allostatic methodology for relaxation and auto-calibration of neural oscillations

Brain and Behavior

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Peer-Reviewed Publications

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Noninvasive neurotechnology from Cereset Research is being studied at the following institutions:

Funding for this research has been provided by independent third parties including but not limited to:

The Susanne Marcus Collins Foundation, Inc., for clinical trials to evaluate HIRREM for migraine, insomnia, and other conditions ($3 million to Wake Forest School of Medicine; 2011 – present).

Office of the Under Secretary of Defense (Acquisition, Technology, and Logistics), to evaluate HIRREM for military personnel with traumatic stress symptoms ($107,000 to Wake Forest School of Medicine; 2014).

United States Army Research Office, to develop Technology to Regulate Circadian Rhythm for Health and Performance, Phase I STTR Award to Brain State Technologies ($150,000; 2014).

US Army Medical Department, Advanced Medical Technology Initiative Rapid Innovation Award to Fort Bragg, Womack Army Medical Center, to evaluate feasibility of wearable brain optimization technology in special operations personnel ($30,000 Womack Army Medical Center; 2017).

Congressionally Directed Medical Research Programs, Psychological Health and Traumatic Brain Injury Research Program, for clinical trials to evaluate closed-loop allostatic neurotechnology for military service members with persisting symptoms after traumatic brain injury (Contract #W81XWH-17-2-0057, $2,833,185 to Brain State Technologies, with sub-awards to Geneva Foundation on behalf of Womack Army Medical Center, and Henry Jackson Foundation on behalf of Uniformed Services University).

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169 Saxony Rd #202
Encinitas, CA 92024

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